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Gnosis by Lesaffre

United States

Gnosis by Lesaffre, a business unit of Lesaffre, is a world expert in yeast, bacteria and pure molecule from fermentation, dedicated to human health and nutrition. The company aspires to be a trusted innovation partner for its clients in the pharmaceutical, nutritional and functional food industries, and to assist them in helping consumers lead healthier and happier lives.


From nutritional and fortified yeasts to yeast fractions, probiotic yeasts and bacteria, vitamin or pure molecules, Gnosis by Lesaffre develops and supplies innovative solutions and ingredients of natural origin with scientifically proven efficacy to target a wide range of applications: digestive health, bone protection, immunity enhancement, joints and liver health, women health, vegetarian support and overall wellbeing. The broad range of differentiating solutions aims at improving and boosting human health by bringing to our diet bioactive nutrients. 


Gnosis by Lesaffre products are designed for dietary supplements, functional foods, drugs or medical devices. Gnosis by Lesaffre is a trustful partner for dietary supplements marketers for decades, remaining the core-business of the business unit. Gnosis by Lesaffre has been able to develop its production practices to produce APIs (Active Pharmaceutical Ingredients) under GMP certification. Gnosis by Lesaffre also offers its expertise in the implementation of its ingredients in functional food applications thanks to its applications lab.   


Gnosis by Lesaffre offers a broad portfolio of ready-to-use solutions of natural origin covering a broad spectrum of applications:


·         Nutritional Yeasts – Lynside®
The Traditional Superfood boosting your overall well-being. Excellent protein and fiber content, naturally rich in B-vitamins, suitable for the whole family, vegan support.


·         Lynside® ProteYn– The Alternative Source Of Complete protein from yeast

Lynside® ProteYn is an innovative ingredient suitable for a variety of dietary lifestyles. Not only Lynside® ProteYn ingredients provide a good protein intake but, unlike many plant-based protein sources, it supplies a range of wholesome components including naturally-occurring fibers, B-vitamins and minerals such as iron, zinc, calcium, magnesium, phosphorus and potassium.


·         Quatrefolic® - The 4th generation folate


  • Quatrefolic®
  • Vitamk7®
  • Lynside® ProteYn
  • K2&Olive®
  • Emothion®
  • Mythocondro®
  • IbSium®
  • Phosphocomplex®
  • Adogran®
  • Nutritional Yeasts - Lynside®
  • Quatreflora™
  • Adonat®
  • Biootic®


Stable salts of S-Adenosylmethionine and process for the preparation thereof
The present invention refers to new salts of S-adenosylmethionine (SAMe) with improved stability and containing at least 70% by weight of SAMe.
Patent Number: US 8,258,115 | Patent Date: 09/04/2012
Process for the preparation of pharmaceutically acceptable salts of (SS-RS)-S-Adenosyl-L-Methionine
The present invention relates to a process for the preparation of pharmaceutically acceptable salts of (R,S)-S-Adenosyl-L-Methionine and allows to obtain the salified ( R)-(+)-S-Adenosyl-L-Methionine diasteroisomer in amounts lower than or equal to 3% with respect to the salified (S)-(+)-S-Adenosyl-L-Methionine diasteroisomer; the salts that can be obtained by the process of the invention keep their configuration stable in time.
Patent Number: US 6,958,233 | Patent Date: 10/25/2005
Process for the preparation of tablets comprising S-Adenosyl-L-Methionine
The present invention provides a process for the preparation of tablets comprising S-Adenosylmethionine and/or a pharmaceutically and/or dietarily acceptable derivative thereof by blending that active component with specified additives, compressing the blend, followed by coating.
Patent Number: US 7,087,587 | Patent Date: 08/08/2006
A process for the preparation of Vitamin K2
A process for the preparation of vitamin K2 (MK-7) comprising the culture of Bacillus subtilis mutant strain GN13/72DSM 17766 deposited on Dec. 5, 2005 at the DSMZ.
Patent Number: US 7,718,407 | Patent Date: 02/22/2010
Folates, compositions and uses thereof
The present invention relates to folates, compositions and uses thereof; In particular, this invention describes a crystalline or amorphous compound which is a substituted or unsubstituted folate or a reduced folate, or the natural or unnatural isomers thereof, of at least one organic base, as well as compositions and uses thereof. The compounds of the invention show a long lasting stability as well as a peculiarly high watr-solubility.
Patent Number: US 7,947,662 | Patent Date: 05/24/2011
Process for producing glutathione
There is disclosed a fermentation process for producing glutathione which comprises (a) the obtainment of a biomass pre-culture by pre-cultivating, in aerobic conditions, a strain of a glutathione producing yeast where in the glutathione content per biomass unit is higher than 1.2% w/w; (b) the cultivation, in aerobic conditions, of the resulting biomass pre-culture such that the resulting biomass density is higher than 50 g/l; (c) the activation of the cultured biomass; and (d) the recovery of the cultured biomass, extracting glutathione at a pH equal to or lower than 6 and purifying the resulting glutathione. The process allows to obtain glutathione with high yields and relatively low costs.
Patent Number: US 6,902,912 | Patent Date: 06/07/2005
Dried or freeze-dried and/or microencapsulated Saccharomyces cerevisiae cells with a high content of (S)-(+)-S-Adenosyl-L-Methionine, process for their preparation, and compositions containing said ce
Disclosed are dried and/or microencapsulated Saccharomyces cerevisiae cells with a high content of (S)-(+)-S-Adenosyl-L-Methionine, in the form of a free base obtainable from selected high-productivity strains of (S)-(+)-SAMe.
Patent Number: US 9,365,817 | Patent Date: 06/14/2016



Lynside Protein™



Nutritional Yeasts - Lynside® Lesaffre Healthy Yeast Inside

Quatrefolic® - The 4th generation folate