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Specialty Enzymes & Probiotics

United States

Specialty Enzymes & Probiotics is a research-driven manufacturer with innovative probiotic and enzyme solutions shown to promote gut, joint and immune health.

We manufacture enzymes from all four natural origins: plant, fungal, microbial and animal, as well as a full line of probiotics.

We offer custom blends, individual enzymes and probiotics in bulk, and scientifically-formulated blends.

Our complete line of probiotics include three shelf-stable, acid-stable Bacillus species, shown to promote a healthy gut microbiome.

Shortest Lead Times * Non-GMO products * Unparalleled Technical Support * 53 years of manufacturing experience * GMP-certified by NSF International


Our founder pioneered a method to extract the enzyme papain from papaya in 1957, and opened the first enzyme manufacturing plant in India one year later. President Vic Rathi brought that same entrepreneurial spirit to North America, and founded Specialty Enzymes & Probiotics in 1985. As one of the world’s foremost enzymologists, he has overseen the development of more than 900 custom enzyme and probiotic solutions in his 40 years of enzyme and probiotic experience.


Probiotics: Our ProbioSEB™ line is formulated to support a favorable environment for the growth of beneficial bacteria in the large intestine.

Our Latest Probiotic Blend: ProbioSEB CSC3™ is a revolutionary, shelf-stable probiotic blend of three spore-forming Bacilli species and prebiotic fructooligosaccharide (FOS) for a healthy gut microbiome.

ProbioSEB CSC3™ is a triple-strength blend with SEBtilis™ (Bacillus subtilis), SEBiotic™ (Bacillus coagulans), and SEBclausii™ (Bacillus clausii), gram-positive bacteria that supports healthy immune function*.

  • SEBclausii™ | Promotes Healthy Gut Microflora During and After Antibiotic Use*
  • SEBtilis™ | Promotes Intestinal Homeostasis*
  • SEBiotic™ | Promotes Recovery from Diarrhea and Constipation*
  • FOS | A Prebiotic to Promote Rapid Growth of Beneficial Bacteria*
  • Stable at Room Temperature*
  • SEBtilis™, SEBiotic™, & SEBclausii™ are Bacillus species, which are encased by a protective endospore to help them survive the journey to the gut, where they thrive*

Digestive Enzymes: Our DigeSEB™ line contains a complete range of digestive enzymes to support the breakdown of carbohydrates, fats, proteins and dairy products into nutrients the body can use.

Systemic Enzymes: We are the world’s largest manufacturer of Serrapeptase, one of the most powerful systemic enzymes available. Our proven and effective systemic enzyme blends include Exclzyme EN™, Serracor™ and SEBkinase™.

Sports Nutrition: Our Prohydroxy P™ and Pepzyme AG™ are complete proteolytic enzyme blends crafted with the most active among us in mind.

Quality Assurance

We combine decades of enzyme and probiotics experience with state-of- the-art technology to deliver FDA cGMP certifiable laboratory testing and third-party certifications.

  • GMP-certified by NSF International
  • Kosher
  • Halal
  • NASC Preferred Supplier


  • ProbioSEB CSC3™
  • DigeSEB™
  • Exclzyme™
  • SEB Gluten Relief™
  • Peptizyme SP™
  • ProbioSEB Duo™/Trio™/Multi™
  • VegPanzyme™
  • Prohydroxy P™
  • ClenzSEB™
  • VegPeptase™
  • HemiSEB™
  • SEBiotic™
  • SEBclausii™
  • SEBtilis™
  • Pepzyme Ag™


  • Institute of Food Technologists (IFT)
  • International Probiotics Association (IPA)
  • Natural Products Association (NPA)
SEBclausii™ contains Bacillus clausii a shelf-stable, spore-forming Bacillus


SEBiotic™ bacillus coagulans


SEBtilis™ (Bacillus subtilis)


ProbioSEB CSC3 a shelf-stable probiotic blend of three spore-forming Bacilli

ProbioSEB CSC3™

DigeSEB™ Blends- Digestive Enzyme Blends

DigeSEB™ Blends

Pepzyme AG - Natural Supplements - Muscle Recovery

Pepzyme AG™

ProhydroxyP- Nutrient Absorption Supplements & Protein Powder Digestive Enzymes

Prohydroxy P™

Peptizyme SP EN - Serratiopeptidase Enzyme

Peptizyme SP EN™

Exclzyme EN - Systemic Enzyme Blend

Exclzyme EN™

ClenzSEB- Probiotic Cleanse, Detox & GI Specialty Enzymes


ProbioSEB™ Duo/Trio/Multi- probiotic blends

ProbioSEB™ Duo/Trio/Multi

SEBGluten Relief - Gluten & Casein Intolerance Digestive Enzymes

SEBGluten Relief™