µsmin®Plus: Bio-enhanced Micronized Diosmin
Proprietary flavonoids complex with enhanced bioavailability.
Diosmin, a citrus flavonoid derived from hesperidin, is used for treating acute internal hemorrhoids, preventing relapse of acute internal hemorrhoids, treating varicose veins, venous stasis, subconjunctival and retinal hemorrhage, lymphedema following breast cancer surgery, venous stasis, and gingival bleeding. Diosmin has also been used to protect against liver toxicity.
Active: diosmin (NLT 90% tot. flavonoids).
Extract Type: micronized granulated powder.
Recommended Dosage: 300 – 900 mg/day.
Applications: powders, tablets, hard shell capsules.
UPS AND FEATURES
Proprietary blend of flavonoids
9x greater absorption than ordinary micronized diosmin
Pre-clinical and clinical pharmacokinetics
Improved conversion in the active aglycone form
With an acid-buffering system
Great flowability and compressibility
SCIENTIFIC EVIDENCE/PROPRIETARY STUDIES
Pharmacokinetic profile of µsmin® Plus, a new micronized diosmin formulation, after oral administration in rats (Russo et al 2015). Comparative Bioavalaibility of Two Diosmin Formulations after Oral Administration to HealthyVolunteers (Russo et al 2018).