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b-2Cool® is a natural ingredient supplying native type II collagen. It is extracted from chicken sternums and manufactured by Bioiberica through a strictly controlled process that preserves the active parts of the molecule. 

The triple helix structure is the active form of the native type II collagen, which allows it to carry out its biological effects.

Type II collagen is the main structural protein in the cartilage, and provides tensile strength and toughness to the tissue.

What is for?

Some joint disorders involving inflammation and cartilage erosion, like Osteoarthritis and Rheumatoid Arthritis, are caused by an immune response against endogenous type II collagen.

Orally taken in its native form, a low dose of type II collagen is able to modulate this immune response through a special immune-mediated mechanism of action called Oral Tolerisation, which consists of a diminished immune response to a previously ingested antigen.

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