Cannabis sativa L. extract (THC< 0.1%) Linnea extracts and manufactures Cannabis as a botanical ingredient for pharmaceutical purposes. A growing number of clinical studies indicates that Cannabis and its phytocannabinoids may have a relevant medicinal value for certain diseases. The mechanisms of action of the single cannabinoids and their interaction in biological human system are also becoming increasingly clear. The discovery of the endocannabinoid system and its physiological functions contribute to understanding a significant potential role of Cannabis in medicine. CBD or cannabidiol, is one of the major non-psychotropic cannabinoid found in Cannabis. It has shown antiepileptic, anti-inflammatory, anti-emetic, muscle relaxing, anxiolytic, neuroprotective and anti-psychotic-like activity and reduces the psychoactive effects of THC (tetrahydrocannabinol).