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Pharma Industry - Superdisintegrants - HiLose

Croscarmellose Sodium (CCS) HiLose TM

Croscarmellose Sodium (CCS) HiLose TM HiloseTM, is an internally cross linked polymer of carboxymethyl cellulose sodium which is used as a super disintegrant in pharmaceutical formulations. Cross Linking makes it insoluble & highly absorbent material, resulting in excellent swelling properties. Its unique fibrous nature gives it excellent water wicking capabilities. Advantages Rapid swelling characteristics Superior flow property Good stability with API Long term stability Fast tablet disintegration Fast drug dissolution Economical Applications Used in oral pharmaceutical formulations as a super disintegrant for Capsules, Tablets and Granules Formulations. Used in tablets including dietary supplements to assist the tablet in disintegrating in the intestinal track. In tablet formulations, it is used in both direct compression and wet granulation processes. Effective in combination with both insoluble filler-binders and slightly soluble to soluble filler-binder. Used in wet granulations as intra granular or extra granular super disintegrant.

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