Natural Ingredients and Products Directory is part of the Informa Markets Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.


CS b-Bioactive® is Bioibérica's chondroitin sulfate for use in nutritional supplements. It is the most well researched chondroitin sulfate on the market, the benchmark and the one of the highest quality.

What are its effects?

A number of clinical trials demonstrate that Chondroitin Sulfate reduces joint pain and improves mobility. It can also control the progress of the disease and recent studies suggest that it can reduce the need for knee prosthesis implants.

Different manufacturing processes and different sources of biological starting material can give rise to chondroitin sulfate molecules with very different chemical-structural properties, especially regarding their content, molecular weight and impurities profile.

The great variability that exists between different chondroitin sulfate molecules can affect the efficacy of the end product: they may have different pharmacokinetic, absorption and even pharmacological properties.

Similarly,this variability in origin and manufacture can affect the safety of the end product and may even have catabolic and negative effects on the joint, cause allergic reactions in the organism, or have other more serious safety problems, such as the presence of viruses or prions.

Bioibérica uses the highest quality raw materials, which, together with its processing method, guarantees chondroitin sulfate 100% richness every time, minimizing the presence of impurities and overcoming the quality requirements of both the European Pharmacopoeia (EP) and the United States Pharmacopoeia (USP).

Bioibérica controls the traceability of all the tons of chondroitin sulfate it produces, up to the slaughterhouse, where it also conducts audits to ensure that GMP standards and other standards for products of animal origin are complied with.

For all these reasons, chondroitin sulfate produced by Biobérica was the standard approved in 2004 by the European Pharmacopoeia as Benchmark Chemical Substance and was also selected in the US by the National Institute of Health (NIH) for the execution of the GAIT clinical trial (Glucosamine/Chondroitin Arthritis Intervention Trial) Furthermore, most clinical trials executed with pharmaceutical grade chondroitin sulfate used Bioibérica's material. For all these reasons, Bioibérica's chondroitin sulfate is of the highest quality and has the most clinical evidence of its efficacy and safety as a treatment for osteoarthritis. 

View this product at