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Fully automated sample analysis and evaluation system for routine quality control

Fully automated sample analysis and evaluation system using HPTLC plates (20 x 10 cm). The HPTLC PRO SYSTEM (patented technology) is best suited for routine quality control of analytes extracted from complex matrices, providing reproducible and reliable results. It supports up to 75 samples, up to five plates, and up to three independent developing solvents without intervention. The possibility of derivatization, MS coupling, and plate storage are included.

APPLICATION:  The samples are applied as bands onto the HPTLC glass plate (20 x 10 cm) with the HPTLC PRO Module APPLICATION. Up to 75 samples can be applied autonomously. Precision of the applied volume, exact positioning and sharpness of applied zones determine the quality of the final result.

DEVELOPMENT:  The HPTLC PRO Module DEVELOPMENT, using HPTLC glass plates (20 x 10 cm), operates completely autonomously. The activity of the stationary phase can be adjusted, and the gas phase can be actively circulated during development (conditioning, regeneration), allowing a better separation of the analytes.

DERIVATIZATION (Expected 2020):  Substances without chromophores or fluorophores can be visualized by automated spraying of specific reagents onto the HPTLC glass plates (20 x 10 cm) with the HPTLC PRO Module DERIVATIZATION, controlled by the HPTLC Software visionCATS. The module features an integrated plate heating unit.

DETECTION (Expected 2021):  Hyperspectral data, acquired with the HPTLC PRO Module DETECTION, are used to characterize and quantify all analytes. They are obtained by using polychromatic light or specific LEDs for excitation together with an imaging spectrometer. The HPTLC Software visionCATS is used for data evaluation.

MS-INTERFACE (Expected 2020):  HPTLC-MS coupling allows for verification of the chemical structure of analytes by Mass Spectrometry or offline collection for further analysis. Any position on the plate can be selected via the HPTLC Software visionCATS to be automatically eluted with the HPTLC PRO Module MS-INTERFACE.

PLATE STORAGE (Expected 2020):  This Module is required to run multiple plates with the HPTLC PRO SYSTEM autonomously. It consists of two closed compartments, one holding up to five new HPTLC glass plates and one up to five finished plates.

SOFTWARE INTEGRATION:  CAMAG’s HPTLC Software visionCATS organizes the workflow of the HPTLC PRO analysis, controls the HPTLC PRO Modules, and manages all data evaluation.


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