Improve Drug Bioavailability & Dissolution Rate
Bioavailability Enhancement Industry estimates indicate that between 60-90% of new chemical entities exhibit poor solubility or dissolution rate. Effectively addressing these issues is essential for the development of drugs with adequate bioavailability, which is crucial if a drug is to provide the desired therapeutic benefit to patients. Capsugel is a leader in drug solubility and enhancement of solubility or dissolution rate. The depth of our bioavailability enhancement technologies makes Capsugel a leader in enhancing drug solubility and drug dissolution rate. We work collaboratively with our customers to apply these technologies to advance compounds with a wide range of properties and delivery challenges. Rather than relying on trial and error, we use a fundamental, model-based approach to select the best technology for each of our customers’ compounds. We build on that approach with formulation optimization, process development, and scale-up to advance medicines first to the clinic and then to commercialization. We provide customers with integrated product development services, from defining the problem to clinical and commercial scale production of micronized APIs / drug product intermediates, using enabling technologies such as spray drying, and/or finished dosage forms.