SupplySide Connect - Food Science & Ingredients Supplier Directory is part of the Informa Markets Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.


KSM-66 is Ixoreal's ashwagandha extract, created via a process that took 14 years of R&D to develop and refine. KSM-66 is the best ashwagandha extract on the world market today in the sense that it is the highest concentration full-spectrum extract available today. A "full-spectrum" extract is an extract which maintains the balance of the various constituents as in the original herb, without over-representing any one constituent. The ashwagandha herb's efficacy is believed to be derived from a complex blend of active constituents, mainly alkaloids like withanine, somniferine, tropine, and steroidal lactones called withanolides. All these constituents need to be present in their natural proportions, which is why it is important for an extract to be full-spectrum. However, producing a high concentration full-spectrum extract is technologically very challenging. Only Ixoreal has managed to create a process that surmounts these challenges, and that too only after many years of R&D. The Ixoreal science team sought to introduce to the world the true quintessence of ashwagandha with all its benefits. Convinced that the essence of the ashwagandha root could be extracted without losing its potency, the science team dedicated itself to learning the nuances of plant chemistry and did what no one was able to achieve until then. With `Green Chemistry` processing, they were able to holistically extract all the root essence while preserving its natural healing potency. This proved to be immensely successful.

KSM-66's extraction process entails pre-treating the ashwagandha roots with milk. For this reason, it contains milk constituents. Such pre-treatment is consistent with the process described by traditional ayurveda healers and texts. However, the traditional process does not scale up very well. Ixoreal has taken this traditional method and refined it greatly so that it produces high quality ashwagandha in a scalable manner, combining the traditional with the modern. Therein lies Ixoreal's "secret sauce", a highly proprietary process that took 14 years to develop and implement. The milk pre-treatment is important in our extraction process because this is in fact what leads to retention of both hydrophilic components and lipophilic components of the raw root, which in turn leads to a full-spectrum extract of such high-potency. For formulators targeting products at consumers who are vegan or for other reasons want to avoid milk, we also have a version of KSM-66 where the milk-pretreatment is skipped: this version of KSM-66 is vegan and milk-free. 

KSM-66 has been clinically proven to be effective. It leads the industry in clinical trials and basic research related to ashwagandha. Ixoreal has conducted numerous clinical studies using KSM-66 Ashwagandha extract in collaboration with major academic and research institutes. All of Ixoreal partnered clinical studies follow gold standards of substantiation: randomized, double-blind, placebo-controlled designs. 

KSM-66 Ashwagandha is standardized to the highest percentage of withanolides in the world, >5% by HPLC, derived only from the roots of the plant. Standardization implies that an extract provides consistent dosage delivery and guaranteed potency. Standardization ensures that manufacturers and formulation developers can use a certain amount of extract and be assured of a commensurate amount of active constituents without much random variation from batch to batch. In addition to the desired quantum of withanolides, the nutrient rich KSM-66 also contains short and long chain amino acids, fructo-oligosaccharides, Vitamin A, calcium and Iron. 

There are several other important ways in which KSM-66 is superior to other extracts for use in nutrition supplement and foods: KSM-66 ashwagandha has superior sensory characteristics and is not bitter. Unlike KSM-66, most other ashwagandha products use hydroalcoholic extraction. An effect of hydroalcoholic extraction is that the end-product is very bitter. In contrast, KSM-66 extract has a pleasant aroma and is neutral in taste, making an excellent choice for use in food and beverages.

View this product at