HU58™ HU58™ is a bacterial spore (of the Bacillus subtilis strain) isolated from the human intestinal tract of healthy volunteers. The product has been well studied and is manufactured under license from Royal Holloway College of the University of London (RHUL). Indications for use include gut health, antibiotic-induced diarrhea, ulcerative colitis, bacterial vaginosis, urinary tract infection (UTI), and candida vaginal infections. Moreover, it can provide a nutritional boost when added to foods (biscuits, breads, dairy products etc.), supplements (tablets, capsules), and beverages for various health applications. HU58™ Bacillus subtilis has been shown in studies to have superior sporulation and germination efficiency. It is stable at extreme pH levels and high temperatures, and can survive dessication, antibiotics, as well as challenging storage/manufacturing conditions, and the gastric environment in the stomach.