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SiliaSphere™- Spherical Silica Gel

SiliCycle is your partner of choice for your purification and chromatography needs. Here is why:

  • Recognized worldwide as a leader with outstanding quality spherical silica gels for analytical and preparative chromatography.
  • One of the best silica on the market with unbeatable performance, superior chromatographic performance, loading capacity, reproducibility, and chemical & physical stability.
  • Broadest portfolio of chromatographic phases to suit all purification needs.
  • Wide range of formats for all purification scales bulk & HPLC columns.

SiliCycle is a World Class Silica Expert

At SiliCycle, we offer two grades of spherical silica gel; SiliaSphere Monodispersed Spherical Silica Gel for analytical needs and SiliaSphere PC for preparative ones. Both grades are manufactured under the same well controlled processes to ensure constant reproducibility and easy scale-up.

With pore diameters ranging from 60 to 1,000 Å and particle sizes from 1.8 to 200 µm, we offer products to meet all your separation requirements. This is one of the most reliable portfolios of spherical silica gels for high pressure chromatography. SiliaSphere are ideal for both analytical and preparative chromatography, from laboratory to pilot-plant processes and production scales. Furthermore, the excellent properties of SiliaSphere make them the packing of choice for high performance liquid chromatography (HPLC), Supercritical Fluid Chromatography (SFC) and simulated moving bed (SMB) applications.

For over 18 years, SiliCycle has been dedicated to silica gel manufacturing and we have achieved a strong know-how and expertise in this field. Furthermore, to support the increasing demand on our spherical silicas, we have developed an optimized and highly controlled large-scale production process for all of our SiliaSphere products without decreasing the quality of the silica.

Particle shape, pore and particle size distributions, silica gel purity, and surface properties, all have their influence on chromatographic performance. Therefore, in order to develop the most efficient process, all previously mentioned parameters need to be evaluated and optimized to ensure batch-to-batch reproducibility.

SiliaSphere is manufactured from an organic form of silicon (alkoxydes). This ensures very low metal content as the starting material is purified by distillation. Deionized water is used to hydrolyze the silicon alkoxydes. Careful monitoring and control of the parameters that induce precipitation afford spherical silica gels with the desired characteristics. SiliaSphere products are characterized by a very low metal content and exceptional stability even at extreme pHs. Furthermore, our manufacturing process ensures quality and reproducibility in pore size, surface area and particle sizes and morphology for all SiliaSphere products.

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